Hello, I am looking for someone to write an essay on The influence of culture conditions on the mechanical properties of agarose hydrogels for cartilage tissue engineering. It needs to be at least 4000 words.
Numerous researches have been conducted with no resolution to some of these fundamental issues, in an effort to characterize the synovial body joints, it has led to the development of an experimental approach to in the investigation of the dynamic and constitutive properties of the cartilage. In a nutshell, the interpretation of this information leads to the illumination of a cartilage microstructure. This cartilage is basically composed of the collagen meshwork under the tension within the osmotic potential composed of a finer proteoglycan network gel. These dynamic properties and constitution of the cartilage are usually determined by this structures motion in the surrounding fluids. In relevant physiologically conditions, this gel networks assumes the state of immobilization to relative collagen networking an equivalent single network referred to as the cartilage network which characterizes the major cartilage behavior. Body energy is basically stored in this cartilage networks in three forms and any external load is usually balanced in the state of equilibrium by the elastic changes of the collagen network and by both osmotic and no osmotic ionic proteoglycan networks potentials of the cartilage network. This state of equilibrium can be distorted or shifted by changing the reference level of the osmotic pressure or by mechanical loading. The majority of biomechanical approaches in the properties of cartilage these are referenced and in mechanical tests, it suffers from the challenges of practical limits in the replica of the situ conditions, especially in the equilibrium. The use of compression specimens is paramount and is plugged from the exercised joints which must be preloaded in achievement of the uniaxial conditions of strain and the poisson effect of the thin and tensile specimens.
In this experiment, the specimen cartilage is first put in a state of equilibrium in a saline solution under controlled temperatures